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To generate endothelial cell specific single IP 3 R1 knockout and triple IP 3 R knockout mice, the 7 to 8 week old iCre IP 3 R1 floxed IP 3 R1 f f and iCre IP 3 R1 f f IP 3 R2 f f IP 3 R3 f f mice were intraperitoneally injected with tamoxifen 50 mg kg per day; Sigma Aldrich for 5 consecutive days, and they were considered as endothelial cell specific IP 3 R1 knockout ECR1KO and endothelial cell specific IP 3 R triple knockout ECTKO mice, respectively <a href=http://cialiss.makeup>buy cialis canada pharmacy</a> |
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